PILOCARPINE HCL 2%, 3%, 4% EYE DROPS CLASS: Ophthalmic.

Caution patient that pilocarpine may cause visual changes, especially at night; avoid driving or other activities requiring alertness until effects of medication are known.

Pilocarpine is in a class of medications called miotics. It works by allowing excess fluid to drain from the eye. How should this medicine be used? Ophthalmic pilocarpine comes as a solution (liquid) to instill in the eyes and as an eye gel to apply to the eyes. The eye drops are usually instilled two to four times daily.

Pilocarpine ophthalmic beads are administered as 1 or 2 beads par dosage, with six beads per twenty-four hours as upper limit recommended dose. Ocular bioavailability of locally applied pilocarpine is merely 0.1-3 % ( Lazare and Horlington, 1975 ) and the drug must be administered as eye-drops three to four times per twenty-four hours which impairs patient conformity ( Kass et al., 1986 ).

In 1 randomized, single-blinded study, pilocarpine 2% ophthalmic solution 4 drops PO 3 times per day for 6 weeks was effective in stimulating salivary flow and relieved xerostomia in patients with Sjogren's syndrome. This dose was approximately equivalent to 2.5 mg 3 times per day. NOTE: The drops were administered orally in this study.

FDA approved prescription drugs for ophthalmology, which are used to treat eye conditions and eye diseases such as glaucoma, conjunctivitis and others. Get an idea about them from this page.

For maximum comfort, an ophthalmic solution should have the same pH as the tears. However, this is not pharmaceutically possible, because at pH 7.4 many drugs are insoluble in water. A few drugs— notably pilocarpine hydrochloride and epinephrine bitartrate—are quite acid and overtax the buffer capacity of the tears.

ISOPTO CARPINE STERILE OPHTHALMIC SOLUTION 2% was registered with Health Science Authority of Singapore by NOVARTIS (SINGAPORE) PTE LTD. It is marketed with the registration number of SIN04712P with effective from 1990-06-13. This product contains 2% of Pilocarpine in the form of SOLUTION.

Patients utilizing ophthalmic beads are confronting with frequent dosing agendas and hard bead instillment. Therefore, the purpose of the present probe was to look into and fix a long permanent pilocarpine loaded chitosan nanoparticles. Nanoparticles were prepared by ionic gelation technique.

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Know about technical details of Pilocarpine Hydrochloride like: chemical name, chemistry structure, formulation, uses, toxicity, action, side effects and more at Pharmacompass.com. Technical details about Pilocarpine Hydrochloride, learn more about the structure, uses, toxicity, action, side effects and more.

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Always use Timolol exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. The usual starting dose is one drop of 0.25% eye drops into each affected eye(s) twice daily, approximately 12 hours apart. Your doctor will change your treatment as necessary.